Genomics of the Pakistani Population: Perspectives on Long-Read Next-Generation Sequencing

Abstract

Pakistan represents one of the most genetically diverse regions in South Asia, yet remains underrepresented in global genomic databases. The advent of long-read next-generation sequencing (NGS) technologies offers unprecedented opportunities to explore this diversity, resolve complex genomic structures, and address pressing health and agricultural challenges. This perspective highlights the potential of long-read sequencing in advancing Pakistani genomics, with
implications for medicine, population genetics, and sustainable development.